ISS

"Since 1984, ISS has been committed to the development and design of highly sensitive scientific instrumentation for research, clinical and industrial applications." "ISS instruments are installed in universities and corporations worldwide. Our customers include several major universities, corporations, hospitals and research institutions across the globe, including, in the United States, The Mayo Foundation, the VA Administration, The National Institute of Standards and Technology, The National Institutes of Health, Oak Ridge National Laboratories and The National Aeronautics and Space Administration (NASA)." "Imagent™ is an instrument for the detection of activated area of the brain under a stimulus. Light is delivered through fiber optics held in place by a headgear; fiber optics bundles collect the optical signal that traversed through the scalp and the brain areas. Up to 64 sources and 16 detectors can be arranged in various geometric patterns to capture, upon activation, both fast signals (a few millisecond long) and slow hemodynamics changes (about 100 milliseconds and longer). While the functional Magnetic Resonance Imaging (fMRI) technique is sensitive only to changes in relative deoxy-hemoglobin concentration (BOLD signal), ImagentT can detect changes in both oxy- and deoxy-hemoglobin concentrations. Tests to prove the co-registration of signals acquired by ImagentT with signals acquired using fMRI have been successfully completed and published."

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