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Zhuang Research Lab
"Understanding the mechanisms of cellular function and their dysfunction in disease requires a detailed picture of the molecular interactions in cells. In particular, we need imaging tools with single-molecule sensitivity, molecular-scale resolution, and dynamic imaging capability to allow direct visualization of molecular interactions in cells, as well as tools that can simultaneously image large numbers of genes, ideally at the genome scale, to probe how collective actions of these molecules give rise to cellular and tissue functions. The research in the Zhuang laboratory is aimed at developing such imaging methods and applying them to problems of biomedical interest."